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Body Fluids and Circulation — NEET Biology MCQs with Solutions

Free NEET Biology Body Fluids and Circulation MCQs with step-by-step solutions covering Blood & Plasma, Formed Elements & Blood Groups, Human Heart & Circulation, Cardiac Cycle & ECG, Circulatory Disorders. Practise online on Prepizo — no login needed.

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Sample questions with solutions

Q1 — Blood & Plasma · easy · theory
The straw-coloured, fluid matrix of blood (about 55% of blood volume) is called:
A. Plasma  ✓ Correct
B. Haemoglobin
C. Serum
D. Lymph
Solution: Plasma is the liquid part of blood (~55%); serum is plasma without clotting factors.
Q2 — Blood & Plasma · easy · theory
The most abundant plasma protein, responsible for maintaining osmotic balance, is:
A. Fibrinogen
B. Globulin
C. Haemoglobin
D. Albumin  ✓ Correct
Solution: Albumins maintain the osmotic (oncotic) pressure; globulins are for defence and fibrinogen for clotting.
Q3 — Formed Elements & Blood Groups · easy · theory
The most abundant blood cells, which carry oxygen and lack a nucleus in humans, are the:
A. Erythrocytes (RBCs)  ✓ Correct
B. Leucocytes (WBCs)
C. Thrombocytes (platelets)
D. Lymphocytes
Solution: RBCs (~5 million/mm³) are enucleate, biconcave and packed with haemoglobin for O₂ transport.
Q4 — Formed Elements & Blood Groups · easy · theory
A person with blood group AB is called a universal ______ because:
A. Recipient; RBCs have no antigens
B. Donor; RBCs have no antigens
C. Recipient; plasma has no anti-A or anti-B antibodies  ✓ Correct
D. Donor; plasma has both antibodies
Solution: AB individuals lack anti-A/anti-B antibodies, so can receive any ABO type — universal recipients.
Q5 — Human Heart & Circulation · easy · theory
The human heart is ______ chambered, with two atria and two ventricles:
A. Four  ✓ Correct
B. Three
C. Five
D. Two
Solution: The human heart has four chambers — two atria (upper) and two ventricles (lower).
Q6 — Human Heart & Circulation · easy · theory
The pacemaker of the heart, which initiates the heartbeat, is the:
A. Atrio-ventricular node
B. Sino-atrial node (SAN)  ✓ Correct
C. Bundle of His
D. Purkinje fibres
Solution: The SA node in the right atrium sets the rhythm — hence "pacemaker".
Q7 — Cardiac Cycle & ECG · easy · theory
The volume of blood pumped out by one ventricle in one heartbeat is the:
A. Cardiac output
B. Residual volume
C. Vital capacity
D. Stroke volume  ✓ Correct
Solution: Stroke volume (~70 mL) is the blood ejected per beat by a ventricle.
Q8 — Cardiac Cycle & ECG · easy · theory
In an ECG, the ______ wave represents the depolarisation of the ventricles:
A. P wave
B. QRS complex  ✓ Correct
C. U wave
D. T wave
Solution: The QRS complex marks ventricular depolarisation (leading to contraction).
Q9 — Circulatory Disorders · easy · theory
Persistently high blood pressure (e.g. above 140/90 mmHg) is called:
A. Hypertension  ✓ Correct
B. Anaemia
C. Hypotension
D. Angina
Solution: Hypertension is high blood pressure (normal ≈ 120/80 mmHg), a major risk factor for heart disease.
Q10 — Circulatory Disorders · easy · theory
Chest pain due to insufficient oxygen reaching the heart muscle is called:
A. Oedema
B. Hypertension
C. Angina (pectoris)  ✓ Correct
D. Leukaemia
Solution: Angina pectoris is acute chest pain from inadequate oxygen supply to the myocardium.
Q11 — Blood & Plasma · easy · numerical
Plasma proteins account for nearly 7% of plasma by weight. If all clotting factors including fibrinogen were removed while the cells stayed intact, the remaining fluid would be best described as:
A. Lymph
B. Blood minus fibrinogen but still containing formed elements — not a standard named fluid  ✓ Correct
C. Serum
D. Tissue fluid
Solution: Serum is the fluid left after clotting, i.e. plasma without fibrinogen and clotting factors — but serum also lacks the formed elements. Since the cells are still present here, it is simply defibrinated blood, not serum.
Q12 — Blood & Plasma · easy · numerical
A patient has severe liver damage that lowers albumin synthesis. The most direct physiological consequence of this fall in plasma albumin is:
A. Oedema due to reduced plasma osmotic (oncotic) pressure  ✓ Correct
B. Rapid blood clotting throughout the body
C. A rise in blood pH to strongly alkaline levels
D. Increased oxygen-carrying capacity of blood
Solution: Albumin is the chief plasma protein maintaining colloid osmotic pressure; its fall lets fluid leak into tissue spaces, causing oedema. It has no role in raising oxygen carriage or clotting.
Q13 — Blood & Plasma · easy · numerical
Which combination correctly pairs a plasma component with its major role?
A. Fibrinogen → osmotic balance; Albumin → defence; Globulins → clotting
B. Albumin → clotting; Fibrinogen → defence; Globulins → osmotic balance
C. Globulins → clotting; Albumin → defence; Fibrinogen → osmotic balance
D. Globulins → defence (antibodies); Fibrinogen → clotting; Albumin → osmotic balance  ✓ Correct
Solution: Globulins are primarily involved in body defence, fibrinogen is needed for clot formation, and albumin maintains the osmotic balance of blood — the standard NCERT pairing.
Q14 — Blood & Plasma · easy · numerical
Roughly 90–92% of plasma is water. Besides proteins, plasma also transports small amounts of which set of substances?
A. Only red blood cells and platelets
B. Only oxygen bound to haemoglobin
C. Bile and pancreatic enzymes exclusively
D. Glucose, amino acids, lipids, and mineral ions such as Na⁺, Ca²⁺, and HCO₃⁻  ✓ Correct
Solution: Plasma carries dissolved nutrients (glucose, amino acids, lipids) and ions (Na⁺, Ca²⁺, HCO₃⁻, etc.). Oxygen is mainly carried by RBC haemoglobin, and cells are formed elements, not dissolved solutes.
Q15 — Formed Elements & Blood Groups · easy · numerical
An anucleate formed element that survives about 120 days and is destroyed mainly in the spleen and liver is the:
A. Neutrophil
B. Lymphocyte
C. Platelet
D. Erythrocyte (RBC)  ✓ Correct
Solution: Mature mammalian RBCs lack a nucleus, live roughly 120 days, and are broken down in the spleen and liver. Platelets live only ~5–9 days and WBCs are nucleated.
Q16 — Formed Elements & Blood Groups · easy · numerical
Which grouping of leucocytes into granulocytes and agranulocytes is entirely correct?
A. Granulocytes: lymphocytes, monocytes; Agranulocytes: neutrophils, basophils, eosinophils
B. Granulocytes: neutrophils, eosinophils, basophils; Agranulocytes: lymphocytes, monocytes  ✓ Correct
C. Granulocytes: monocytes, basophils; Agranulocytes: neutrophils, lymphocytes
D. Granulocytes: neutrophils, lymphocytes; Agranulocytes: eosinophils, monocytes
Solution: Neutrophils, eosinophils, and basophils have cytoplasmic granules (granulocytes); lymphocytes and monocytes lack prominent granules (agranulocytes).
Q17 — Formed Elements & Blood Groups · easy · numerical
A person with blood group O who is Rh negative can safely DONATE packed red cells to which of the following in an emergency?
A. Any Rh positive person but no Rh negative person
B. A recipient of any ABO group who is Rh negative  ✓ Correct
C. Only AB positive individuals
D. Only other O negative individuals under all circumstances
Solution: O negative red cells carry neither A, B, nor Rh(D) antigens, so they can be given to recipients of any ABO group provided they are also Rh negative (or, for RBCs, to Rh positive recipients too). Restricting to only O negative is unnecessary for the cells.
Q18 — Formed Elements & Blood Groups · easy · numerical
Normal counts in adult human blood are approximately:
A. RBC 8000/mm³, WBC 3.5 lakh/mm³, platelets 5 million/mm³
B. RBC 1.5–3.5 lakh/mm³, WBC 5 million/mm³, platelets 8000/mm³
C. RBC 6000–8000/mm³, WBC 5–5.5 million/mm³, platelets 120/mm³
D. RBC 5–5.5 million/mm³, WBC 6000–8000/mm³, platelets 1.5–3.5 lakh/mm³  ✓ Correct
Solution: Standard NCERT values are ~5–5.5 million RBC/mm³, 6000–8000 WBC/mm³, and 1.5–3.5 lakh platelets/mm³.
Q19 — Human Heart & Circulation · easy · numerical
Blood returning from the body tissues enters the human heart first at the:
A. Right atrium via the superior and inferior venae cavae  ✓ Correct
B. Right ventricle via the pulmonary artery
C. Left atrium via the pulmonary veins
D. Left ventricle via the aorta
Solution: Deoxygenated systemic blood returns through the venae cavae into the right atrium. The pulmonary veins carry oxygenated blood into the left atrium.
Q20 — Human Heart & Circulation · easy · numerical
The correct sequence of the cardiac impulse-conducting pathway is:
A. SAN → AVN → bundle of His → bundle branches → Purkinje fibres  ✓ Correct
B. Bundle of His → SAN → AVN → Purkinje fibres
C. AVN → SAN → Purkinje fibres → bundle of His
D. Purkinje fibres → bundle branches → AVN → SAN
Solution: The impulse originates at the SAN (pacemaker), passes to the AVN, then along the bundle of His and its branches, and finally through the Purkinje fibres to the ventricular muscle.
Q21 — Human Heart & Circulation · easy · numerical
The term "double circulation" in humans specifically means that:
A. The heart has two chambers that beat alternately
B. There are two hearts working in parallel
C. Blood passes through the heart twice to complete one full body circuit  ✓ Correct
D. Blood flows in two directions within the same vessel
Solution: In double circulation blood travels through the heart twice per complete circuit — once via the pulmonary loop and once via the systemic loop — keeping oxygenated and deoxygenated streams separate.
Q22 — Human Heart & Circulation · easy · numerical
The left atrioventricular valve of the human heart, guarding the opening between the left atrium and left ventricle, is the:
A. Pulmonary semilunar valve
B. Aortic semilunar valve
C. Bicuspid (mitral) valve  ✓ Correct
D. Tricuspid valve
Solution: The left AV valve has two cusps and is the bicuspid or mitral valve; the tricuspid (three cusps) guards the right AV opening.
Q23 — Cardiac Cycle & ECG · easy · numerical
If an adult has a heart rate of 72 beats per minute and a stroke volume of about 70 mL, the cardiac output is approximately:
A. About 0.5 litre per minute
B. About 1 litre per minute
C. About 72 litres per minute
D. About 5 litres per minute  ✓ Correct
Solution: Cardiac output = heart rate × stroke volume = 72 × 70 mL ≈ 5040 mL ≈ 5 L/min, the normal resting value.
Q24 — Cardiac Cycle & ECG · easy · numerical
In a normal ECG, the QRS complex represents:
A. Depolarisation of the ventricles, just before their contraction  ✓ Correct
B. Repolarisation of the ventricles
C. Closure of the semilunar valves
D. Depolarisation of the atria only
Solution: The QRS complex marks ventricular depolarisation, which initiates ventricular contraction (systole). Ventricular repolarisation is the T wave.
Q25 — Cardiac Cycle & ECG · easy · numerical
The first heart sound, "lubb", is produced by the:
A. Closure of the atrioventricular (tricuspid and bicuspid) valves at the start of ventricular systole  ✓ Correct
B. Contraction of the atria during diastole
C. Closure of the semilunar valves at the end of ventricular systole
D. Opening of the semilunar valves during systole
Solution: The "lubb" (first sound) is caused by closure of the AV valves as the ventricles begin to contract; the "dupp" (second sound) is due to semilunar valve closure.
Q26 — Cardiac Cycle & ECG · easy · numerical
Stroke volume is best defined as the volume of blood:
A. Pumped out by each ventricle during one heartbeat  ✓ Correct
B. Remaining in the ventricle after contraction
C. Returned to the atria from the veins per minute
D. Pumped by both ventricles together in one minute
Solution: Stroke volume is the amount of blood ejected by a ventricle in a single beat (~70 mL). The one-minute output of a ventricle is the cardiac output.
Q27 — Circulatory Disorders · easy · numerical
A person repeatedly records a blood pressure of 150/95 mm Hg. This condition is termed:
A. Normal blood pressure
B. Hypotension (low blood pressure)
C. Angina pectoris
D. Hypertension (high blood pressure)  ✓ Correct
Solution: A sustained BP of 140/90 mm Hg or higher is classed as hypertension; 150/95 clearly exceeds this threshold.
Q28 — Circulatory Disorders · easy · numerical
The symptom of acute chest pain that appears when the heart muscle does not receive enough oxygen-rich blood is called:
A. Angina pectoris  ✓ Correct
B. Leukaemia
C. Atherosclerosis
D. Erythroblastosis
Solution: Angina pectoris is the chest pain resulting from inadequate oxygen supply to the myocardium, often when coronary flow is reduced.
Q29 — Circulatory Disorders · easy · numerical
Deposition of calcium, fat, cholesterol, and fibrous tissue that narrows and hardens the arteries is known as:
A. Thrombocytopenia
B. Atherosclerosis  ✓ Correct
C. Hypertension
D. Anaemia
Solution: Atherosclerosis is the build-up of calcium, fat, cholesterol, and fibrous tissue in the arterial walls, narrowing the lumen and reducing blood flow.
Q30 — Circulatory Disorders · easy · numerical
Coronary artery disease (CAD) is dangerous primarily because the affected vessels:
A. Drain deoxygenated blood from the brain
B. Connect the two atria of the heart
C. Carry blood only to the kidneys
D. Supply blood to the heart muscle itself  ✓ Correct
Solution: CAD affects the coronary arteries that nourish the cardiac muscle; their narrowing starves the myocardium of oxygen, which can lead to angina or a heart attack.