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Body Fluids and Circulation — NEET Biology MCQs with Solutions

Free NEET Biology Body Fluids and Circulation MCQs with step-by-step solutions covering Blood & Plasma, Formed Elements & Blood Groups, Human Heart & Circulation, Cardiac Cycle & ECG, Circulatory Disorders. Practise online on Prepizo — no login needed.

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Sample questions with solutions

Q1 — Blood & Plasma · easy · theory
The straw-coloured, fluid matrix of blood (about 55% of blood volume) is called:
A. Plasma  ✓ Correct
B. Haemoglobin
C. Serum
D. Lymph
Solution: Plasma is the liquid part of blood (~55%); serum is plasma without clotting factors.
Q2 — Blood & Plasma · easy · theory
The most abundant plasma protein, responsible for maintaining osmotic balance, is:
A. Fibrinogen
B. Globulin
C. Haemoglobin
D. Albumin  ✓ Correct
Solution: Albumins maintain the osmotic (oncotic) pressure; globulins are for defence and fibrinogen for clotting.
Q3 — Formed Elements & Blood Groups · easy · theory
The most abundant blood cells, which carry oxygen and lack a nucleus in humans, are the:
A. Erythrocytes (RBCs)  ✓ Correct
B. Leucocytes (WBCs)
C. Thrombocytes (platelets)
D. Lymphocytes
Solution: RBCs (~5 million/mm³) are enucleate, biconcave and packed with haemoglobin for O₂ transport.
Q4 — Formed Elements & Blood Groups · easy · theory
A person with blood group AB is called a universal ______ because:
A. Recipient; RBCs have no antigens
B. Donor; RBCs have no antigens
C. Recipient; plasma has no anti-A or anti-B antibodies  ✓ Correct
D. Donor; plasma has both antibodies
Solution: AB individuals lack anti-A/anti-B antibodies, so can receive any ABO type — universal recipients.
Q5 — Human Heart & Circulation · easy · theory
The human heart is ______ chambered, with two atria and two ventricles:
A. Four  ✓ Correct
B. Three
C. Five
D. Two
Solution: The human heart has four chambers — two atria (upper) and two ventricles (lower).
Q6 — Human Heart & Circulation · easy · theory
The pacemaker of the heart, which initiates the heartbeat, is the:
A. Atrio-ventricular node
B. Sino-atrial node (SAN)  ✓ Correct
C. Bundle of His
D. Purkinje fibres
Solution: The SA node in the right atrium sets the rhythm — hence "pacemaker".
Q7 — Cardiac Cycle & ECG · easy · theory
The volume of blood pumped out by one ventricle in one heartbeat is the:
A. Cardiac output
B. Residual volume
C. Vital capacity
D. Stroke volume  ✓ Correct
Solution: Stroke volume (~70 mL) is the blood ejected per beat by a ventricle.
Q8 — Cardiac Cycle & ECG · easy · theory
In an ECG, the ______ wave represents the depolarisation of the ventricles:
A. P wave
B. QRS complex  ✓ Correct
C. U wave
D. T wave
Solution: The QRS complex marks ventricular depolarisation (leading to contraction).
Q9 — Circulatory Disorders · easy · theory
Persistently high blood pressure (e.g. above 140/90 mmHg) is called:
A. Hypertension  ✓ Correct
B. Anaemia
C. Hypotension
D. Angina
Solution: Hypertension is high blood pressure (normal ≈ 120/80 mmHg), a major risk factor for heart disease.
Q10 — Circulatory Disorders · easy · theory
Chest pain due to insufficient oxygen reaching the heart muscle is called:
A. Oedema
B. Hypertension
C. Angina (pectoris)  ✓ Correct
D. Leukaemia
Solution: Angina pectoris is acute chest pain from inadequate oxygen supply to the myocardium.
Q11 — Blood & Plasma · hard · theory
Serum differs from plasma in that serum:
A. Has more clotting factors
B. Lacks all proteins
C. Contains blood cells
D. Lacks clotting factors (fibrinogen)  ✓ Correct
Solution: Serum = plasma minus the clotting proteins (fibrinogen and others consumed during clotting).
Q12 — Blood & Plasma · hard · theory
Plasma without formed elements contains ~90–92% water and important ions including:
A. Only proteins
B. Only oxygen
C. Na⁺, Ca²⁺, Mg²⁺, HCO₃⁻ and Cl⁻  ✓ Correct
D. Only glucose
Solution: Plasma carries minerals (Na⁺, Ca²⁺, Mg²⁺, bicarbonate, chloride), glucose, amino acids, lipids and proteins.
Q13 — Formed Elements & Blood Groups · hard · theory
Erythroblastosis foetalis occurs when:
A. An Rh⁻ mother carries an Rh⁺ foetus and her anti-Rh antibodies attack the foetal RBCs  ✓ Correct
B. Both parents are Rh⁻
C. An Rh⁺ mother carries an Rh⁻ foetus
D. The foetus is blood group O
Solution: In a second Rh⁺ pregnancy, maternal anti-Rh antibodies cross the placenta and destroy foetal RBCs.
Q14 — Formed Elements & Blood Groups · hard · theory
The formed elements of blood are produced (haematopoiesis) mainly in the ______ in adults:
A. Red bone marrow  ✓ Correct
B. Spleen only
C. Liver
D. Thymus only
Solution: In adults, red bone marrow is the main site of blood cell formation.
Q15 — Human Heart & Circulation · hard · theory
The correct path of the electrical impulse in the heart is:
A. SA node → AV node → bundle of His → Purkinje fibres  ✓ Correct
B. Purkinje fibres → SA node → AV node
C. Bundle of His → SA node → AV node
D. AV node → SA node → Purkinje fibres
Solution: The impulse spreads SAN → AVN → bundle of His → its branches → Purkinje fibres, contracting the ventricles.
Q16 — Human Heart & Circulation · hard · theory
The vena cava carries ______ blood to the ______, while the pulmonary vein carries ______ blood to the ______:
A. Deoxygenated; left atrium; oxygenated; right atrium
B. Oxygenated; left atrium; deoxygenated; right atrium
C. Deoxygenated; right atrium; oxygenated; left atrium  ✓ Correct
D. Oxygenated; right atrium; deoxygenated; left atrium
Solution: Venae cavae bring deoxygenated blood to the right atrium; pulmonary veins bring oxygenated blood to the left atrium.
Q17 — Cardiac Cycle & ECG · hard · theory
The first heart sound "lubb" is produced by the closure of the ______ valves at the start of ventricular systole:
A. Semilunar
B. Mitral only
C. Atrioventricular (bicuspid and tricuspid)  ✓ Correct
D. Aortic and pulmonary
Solution: "Lubb" (S1) = closure of AV valves (systole begins); "dup" (S2) = closure of semilunar valves (systole ends).
Q18 — Cardiac Cycle & ECG · hard · theory
If a person has a heart rate of 75 beats/min and a stroke volume of 70 mL, the cardiac output is:
A. 5.25 L/min  ✓ Correct
B. 52.5 L/min
C. 1.05 L/min
D. 145 mL/min
Solution: CO = 75 × 70 = 5250 mL/min = 5.25 L/min.
Q19 — Circulatory Disorders · hard · theory
A "heart attack" (myocardial infarction) occurs when:
A. The heart beats too slowly
B. The valves leak slightly
C. Blood supply to a part of the heart muscle is blocked, causing muscle death  ✓ Correct
D. Blood pressure drops suddenly
Solution: A blocked coronary artery deprives cardiac muscle of oxygen, causing its death (infarction).
Q20 — Circulatory Disorders · hard · theory
The normal human blood pressure is about ______; the higher value represents ______ pressure:
A. 120/80 mmHg; systolic  ✓ Correct
B. 80/120 mmHg; diastolic
C. 100/60 mmHg; systolic
D. 140/100 mmHg; diastolic
Solution: Normal BP ≈ 120/80 mmHg — 120 (systolic, ventricular contraction) over 80 (diastolic, relaxation).
Q21 — Blood & Plasma · medium · theory
The plasma proteins fibrinogen, globulins and albumins are chiefly involved in, respectively:
A. Osmotic balance, clotting and defence
B. Clotting, defence and osmotic balance  ✓ Correct
C. Defence, clotting and transport
D. Transport, defence and clotting
Solution: Fibrinogen → clotting; globulins → immune defence; albumins → osmotic balance.
Q22 — Blood & Plasma · medium · theory
Blood is considered a ______ tissue because:
A. Nervous; it conducts impulses
B. Muscular; it contracts
C. Connective; it has a fluid matrix (plasma) with cells  ✓ Correct
D. Epithelial; it lines cavities
Solution: Blood is a fluid connective tissue — formed elements (cells) suspended in a plasma matrix.
Q23 — Formed Elements & Blood Groups · medium · theory
The granulocyte most abundant among WBCs, phagocytic and the first to reach infection sites, is the:
A. Basophil
B. Eosinophil
C. Lymphocyte
D. Neutrophil  ✓ Correct
Solution: Neutrophils (~60–65% of WBCs) are phagocytic and combat infection; lymphocytes handle immunity.
Q24 — Formed Elements & Blood Groups · medium · theory
A person with blood group O is the universal donor because their RBCs:
A. Have Rh antigen only
B. Have no antibodies
C. Have both A and B antigens
D. Have neither A nor B antigens  ✓ Correct
Solution: O-group RBCs carry no A/B surface antigens, so they can be given to any ABO recipient.
Q25 — Human Heart & Circulation · medium · theory
The valve between the left atrium and left ventricle is the:
A. Tricuspid valve
B. Bicuspid (mitral) valve  ✓ Correct
C. Aortic valve
D. Semilunar valve
Solution: The left AV opening has a bicuspid (mitral) valve; the right has a tricuspid valve.
Q26 — Human Heart & Circulation · medium · theory
Double circulation in mammals means blood passes through the heart ______ per complete cycle:
A. Twice (pulmonary + systemic circuits)  ✓ Correct
B. Four times
C. Once
D. Three times
Solution: Blood flows heart → lungs → heart (pulmonary) and heart → body → heart (systemic) — passing the heart twice.
Q27 — Cardiac Cycle & ECG · medium · theory
Cardiac output is calculated as:
A. Stroke volume + heart rate
B. Heart rate ÷ stroke volume
C. Stroke volume − heart rate
D. Stroke volume × heart rate  ✓ Correct
Solution: Cardiac output = stroke volume × heart rate (~70 mL × 72/min ≈ 5 L/min).
Q28 — Cardiac Cycle & ECG · medium · theory
The P wave of an ECG corresponds to the ______, and the T wave to the ______:
A. Atrial depolarisation; ventricular repolarisation  ✓ Correct
B. Ventricular contraction; atrial relaxation
C. Atrial repolarisation; ventricular depolarisation
D. Ventricular repolarisation; atrial depolarisation
Solution: P = atrial depolarisation; QRS = ventricular depolarisation; T = ventricular repolarisation.
Q29 — Circulatory Disorders · medium · theory
The deposition of calcium, fat and fibrous tissue narrowing the arteries is called:
A. Anaemia
B. Thrombosis of lymph
C. Atherosclerosis  ✓ Correct
D. Arteriosclerosis of veins
Solution: Atherosclerosis narrows/hardens arteries, raising blood pressure and risk of coronary artery disease.
Q30 — Circulatory Disorders · medium · theory
Coronary Artery Disease (CAD) affects the vessels that supply blood to the:
A. Kidneys
B. Lungs
C. Brain
D. Heart muscle (myocardium)  ✓ Correct
Solution: CAD (atherosclerosis) narrows the coronary arteries that supply the heart muscle itself.